CMap Candidate Details

Structure:
CMap ID: C28681
Pert ID: BRD-K82731415
Compound Name: olomoucine
Targets: CDK2; CDK5; CDK1
MoA: CDK inhibitor
SMILES: Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12
InchiKey: GTVPOLSIJWJJNY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3057 BRD-K82731415 HA1E 10 uM 6 h -0.26 -1.08 0.28 0.0 0.0 0.0
3268 BRD-K82731415 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3548 BRD-K82731415 PC3 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
3874 BRD-K82731415 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39197 BRD-K82731415 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39350 BRD-K82731415 A549 10 uM 24 h -0.29 -1.2 0.55 -0.32 -1.06 0.74
39786 BRD-K82731415 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40343 BRD-K82731415 HT29 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
40645 BRD-K82731415 MCF??7.00 10 uM 6 h 0.27 1.14 0.32 0.0 0.0 0.0
40885 BRD-K82731415 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41206 BRD-K82731415 NPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
41545 BRD-K82731415 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).