CMap Candidate Details

Structure:
CMap ID: C28772
Pert ID: BRD-K82983861
Compound Name: GW-0742
Targets: PPARD
MoA: Insulin sensitizer; PPAR receptor agonist
SMILES: Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(c(F)c1)C(F)(F)F
InchiKey: HWVNEWGKWRGSRK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2929 BRD-K82983861 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
3270 BRD-K82983861 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3549 BRD-K82983861 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3983 BRD-K82983861 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44450 BRD-K82983861 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44624 BRD-K82983861 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45038 BRD-K82983861 ASC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.06
45327 BRD-K82983861 HEPG2 10 uM 6 h -0.26 -1.08 0.31 0.35 1.25 1.29
45585 BRD-K82983861 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45851 BRD-K82983861 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46150 BRD-K82983861 NPC 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
46465 BRD-K82983861 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46791 BRD-K82983861 SKB 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).