CMap Candidate Details

Structure:
CMap ID: C28782
Pert ID: BRD-K83010055
Compound Name: VU-0415374-1
Targets: GRM4
MoA: Glutamate receptor modulator
SMILES: COc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl
InchiKey: RZZCVJKQCRSTKD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19158 BRD-K83010055 A375 10 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.07
19510 BRD-K83010055 A549 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
19806 BRD-K83010055 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20131 BRD-K83010055 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20467 BRD-K83010055 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.38 1.35 1.72
20778 BRD-K83010055 HT29 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.5
21139 BRD-K83010055 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21320 BRD-K83010055 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21648 BRD-K83010055 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).