CMap Candidate Details
Structure:
CMap ID: | C28799 |
Pert ID: | BRD-K83057217 |
Compound Name: | doxifluridine |
Targets: | TYMS |
MoA: | Thymidylate synthase inhibitor |
SMILES: | C[C@H]1O[C@H]([C@@H](O)[C@@H]1O)n1cc(F)c(=O)[nH]c1=O |
InchiKey: | ZWAOHEXOSAUJHY-YQHTUYAKSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
96615 | BRD-K83057217 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
126032 | BRD-K83057217 | HELA | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.76 | 0.07 |
126055 | BRD-K83057217 | HT29 | 0.04 uM | 24 h | 0.18 | 0.75 | 0.0 | 0.0 | 0.0 | 0.0 |
126132 | BRD-K83057217 | JURKAT | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
126185 | BRD-K83057217 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
126222 | BRD-K83057217 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.22 |
126303 | BRD-K83057217 | THP1 | 10 uM | 24 h | 0.24 | 1.02 | 0.12 | 0.27 | 0.94 | 0.3 |
134039 | BRD-K83057217 | A549 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
134068 | BRD-K83057217 | HA1E | 0.03 uM | 24 h | 0.24 | 1.02 | 0.12 | -0.19 | -0.65 | 0.01 |
134106 | BRD-K83057217 | HEK293 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
134207 | BRD-K83057217 | HUVEC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
134260 | BRD-K83057217 | MDAMB231 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
134287 | BRD-K83057217 | PC3 | 0.01 uM | 24 h | 0.28 | 1.16 | 0.36 | 0.0 | 0.0 | 0.0 |
134315 | BRD-K83057217 | YAPC | 0.01 uM | 24 h | 0.27 | 1.13 | 0.28 | -0.27 | -0.92 | 0.33 |