CMap Candidate Details

Structure:
CMap ID: C00288
Pert ID: BRD-A11170096
Compound Name: pravastatin
Targets: HMGCR
MoA: HMGCR inhibitor
SMILES: CCC(C)C(=O)OC1CC(O)C=C2C=CC(C)C(CCC(O)CC(O)CC(O)=O)C12
InchiKey: TUZYXOIXSAXUGO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49931 BRD-A11170096 A549 10 uM 6 h -0.2 -0.83 0.0 -0.25 -0.85 0.19
50095 BRD-A11170096 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50280 BRD-A11170096 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50449 BRD-A11170096 HT29 10 uM 6 h -0.2 -0.85 0.01 0.0 0.0 0.0
50973 BRD-A11170096 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95819 BRD-A11170096 A375 0.74 uM 6 h -0.23 -0.97 0.11 0.0 0.0 0.0
95844 BRD-A11170096 NPC 0.74 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.19
95877 BRD-A11170096 MCF??7.00 0.74 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95886 BRD-A11170096 YAPC 0.74 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95960 BRD-A11170096 PC3 0.74 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.62
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).