CMap Candidate Details
Structure:
| CMap ID: | C28830 |
| Pert ID: | BRD-K83153774 |
| Compound Name: | mirtazapine |
| Targets: | ADRA2A; ADRA2B; ADRA2C; HTR2A; HTR2C; HTR3A |
| MoA: | Serotonin receptor antagonist; Adrenergic receptor antagonist |
| SMILES: | CN1CCN2[C@@H](C1)c3ccccc3Cc4cccnc24 |
| InchiKey: | RONZAEMNMFQXRA-INIZCTEOSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49898 | BRD-K83153774 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50247 | BRD-K83153774 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50420 | BRD-K83153774 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50596 | BRD-K83153774 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50785 | BRD-K83153774 | MCF??7.00 | 10 uM | 6 h | -0.22 | -0.93 | 0.07 | 0.0 | 0.0 | 0.0 |
| 50866 | BRD-K83153774 | PC3 | 10 uM | 24 h | -0.23 | -0.97 | 0.11 | -0.22 | -0.73 | 0.05 |
| 51073 | BRD-K83153774 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.86 | 0.22 |