CMap Candidate Details

Structure:
CMap ID: C28838
Pert ID: BRD-K83186168
Compound Name: AZD-1981
Targets: --
MoA: --
SMILES: CC(=O)Nc1cccc2n(CC(O)=O)c(C)c(Sc3ccc(Cl)cc3)c12
InchiKey: JWYIGNODXSRKGP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125560 BRD-K83186168 A375 1.11 uM 24 h -0.24 -1.02 0.17 0.25 0.88 0.19
125664 BRD-K83186168 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125688 BRD-K83186168 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125708 BRD-K83186168 HUVEC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125761 BRD-K83186168 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.13
125816 BRD-K83186168 MCF??7.00 0.04 uM 24 h 0.26 1.09 0.23 -0.19 -0.64 0.01
125907 BRD-K83186168 YAPC 3.33 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
133656 BRD-K83186168 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133682 BRD-K83186168 HA1E 2.22 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
133722 BRD-K83186168 HEK293 0.03 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
133841 BRD-K83186168 MCF10A 0.03 uM 24 h -0.34 -1.43 1.43 0.0 0.0 0.0
133898 BRD-K83186168 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
133932 BRD-K83186168 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133962 BRD-K83186168 THP1 0.03 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).