CMap Candidate Details

Structure:
CMap ID: C28866
Pert ID: BRD-K83289131
Compound Name: CAY-10618
Targets: NAMPT
MoA: NAMPT inhibitor
SMILES: O=C(CCCCCCCn1cc(nn1)-c1cccnc1)Nc1ccccc1-c1ccccc1
InchiKey: SJOLTIOPWDLDEB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8996 BRD-K83289131 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9243 BRD-K83289131 A549 10 uM 6 h 0.21 0.89 0.02 -0.42 -1.41 2.02
9525 BRD-K83289131 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9830 BRD-K83289131 H1299 10 uM 6 h 0.29 1.22 0.48 0.0 0.0 0.0
10086 BRD-K83289131 HA1E 10 uM 6 h 0.17 0.71 0.0 0.0 0.0 0.0
10125 BRD-K83289131 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10608 BRD-K83289131 HCT116 10 uM 6 h -0.2 -0.85 0.01 0.0 0.0 0.0
10862 BRD-K83289131 HEPG2 10 uM 6 h -0.29 -1.22 0.62 0.0 0.0 0.0
11024 BRD-K83289131 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11304 BRD-K83289131 MCF??7.00 10 uM 6 h 0.23 0.98 0.09 0.0 0.0 0.0
11592 BRD-K83289131 NCIH2073 10 uM 6 h -0.27 -1.14 0.42 0.28 1.0 0.42
11853 BRD-K83289131 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12150 BRD-K83289131 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.67 0.02
12631 BRD-K83289131 PC3 10 uM 6 h 0.17 0.71 0.0 0.32 1.14 0.87
12883 BRD-K83289131 SW480 10 uM 6 h 0.21 0.87 0.01 0.0 0.0 0.0
12942 BRD-K83289131 THP1 10 uM 6 h 0.25 1.03 0.14 0.27 0.96 0.34
13373 BRD-K83289131 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13690 BRD-K83289131 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96049 BRD-K83289131 PHH 1.11 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).