CMap Candidate Details

Structure:
CMap ID: C29023
Pert ID: BRD-K83794243
Compound Name: palovarotene
Targets: RARG
MoA: Retinoid receptor agonist
SMILES: CC1(C)CCC(C)(C)c2cc(C=Cc3ccc(cc3)C(O)=O)c(Cn3cccn3)cc12
InchiKey: YTFHCXIPDIHOIA-DHZHZOJOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126056 BRD-K83794243 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126086 BRD-K83794243 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.97
126134 BRD-K83794243 JURKAT 10 uM 24 h -0.28 -1.18 0.5 -0.26 -0.86 0.21
126186 BRD-K83794243 MCF10A 10 uM 24 h -0.25 -1.04 0.21 0.23 0.8 0.08
126241 BRD-K83794243 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126267 BRD-K83794243 PC3 10 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
126305 BRD-K83794243 THP1 10 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
134011 BRD-K83794243 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134041 BRD-K83794243 A549 0.25 uM 24 h -0.29 -1.22 0.61 0.0 0.0 0.0
134069 BRD-K83794243 HA1E 0.74 uM 24 h 0.0 0.0 0.0 -0.53 -1.77 15.65
134108 BRD-K83794243 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134153 BRD-K83794243 HELA 2.22 uM 24 h -0.21 -0.86 0.02 -0.36 -1.22 1.24
134231 BRD-K83794243 MCF??7.00 0.08 uM 24 h 0.31 1.29 0.64 -0.31 -1.03 0.64
134317 BRD-K83794243 YAPC 0.08 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).