CMap Candidate Details

Structure:
CMap ID: C29024
Pert ID: BRD-K83794624
Compound Name: pirarubicin
Targets: TOP2A
MoA: Topoisomerase inhibitor
SMILES: COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O[C@@H]6CCCCO6)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
InchiKey: KMSKQZKKOZQFFG-YXRRJAAWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33548 BRD-K83794624 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33848 BRD-K83794624 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34191 BRD-K83794624 ASC 10 uM 24 h -0.2 -0.82 0.0 -0.28 -0.95 0.42
34432 BRD-K83794624 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34697 BRD-K83794624 HCC515 10 uM 6 h 0.0 0.0 0.0 0.34 1.22 1.15
34973 BRD-K83794624 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35214 BRD-K83794624 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35388 BRD-K83794624 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35849 BRD-K83794624 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36003 BRD-K83794624 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36363 BRD-K83794624 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36661 BRD-K83794624 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37010 BRD-K83794624 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).