CMap Candidate Details

Structure:
CMap ID: C29117
Pert ID: BRD-K84085265
Compound Name: CG-930
Targets: MAPK8
MoA: JNK inhibitor
SMILES: O[C@H]1CC[C@H](CC1)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n([C@@H]3CCOC3)c2n1
InchiKey: IBGLGMOPHJQDJB-MCIONIFRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33567 BRD-K84085265 A375 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
33849 BRD-K84085265 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34194 BRD-K84085265 ASC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.09 0.85
34435 BRD-K84085265 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34701 BRD-K84085265 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34978 BRD-K84085265 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35217 BRD-K84085265 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35628 BRD-K84085265 NEU 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
35852 BRD-K84085265 NPC 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
36004 BRD-K84085265 PC3 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.99
36368 BRD-K84085265 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36666 BRD-K84085265 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36882 BRD-K84085265 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91555 BRD-K84085265 BT20 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91612 BRD-K84085265 HS578T 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91625 BRD-K84085265 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91667 BRD-K84085265 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91699 BRD-K84085265 MDAMB231 10 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
91779 BRD-K84085265 SKBR3 10 uM 6 h 0.0 0.0 0.0 0.38 1.33 1.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).