CMap Candidate Details

Structure:
CMap ID: C29120
Pert ID: BRD-K84091759
Compound Name: candesartan
Targets: AGTR1
MoA: Angiotensin receptor antagonist
SMILES: CCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InchiKey: HTQMVQVXFRQIKW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52203 BRD-K84091759 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91138 BRD-K84091759 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
95313 BRD-K84091759 A549 10 uM 48 h 0.0 0.0 0.0 -0.31 -1.05 0.7
95455 BRD-K84091759 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
126009 BRD-K84091759 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126088 BRD-K84091759 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126135 BRD-K84091759 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.07
126188 BRD-K84091759 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
126268 BRD-K84091759 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126306 BRD-K84091759 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126344 BRD-K84091759 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134012 BRD-K84091759 A375 0.03 uM 24 h 0.21 0.86 0.01 0.27 0.94 0.3
134110 BRD-K84091759 HEK293 0.74 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
134155 BRD-K84091759 HELA 0.01 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
134185 BRD-K84091759 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134263 BRD-K84091759 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.85
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).