CMap Candidate Details

Structure:
CMap ID: C29147
Pert ID: BRD-K84163249
Compound Name: ercalcitriol
Targets: VDR
MoA: Vitamin D receptor agonist
SMILES: C[C@H](C=C[C@H](C)C(C)(C)O)[C@H]1CC[C@@H]2[C@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
InchiKey: ZGLHBRQAEXKACO-XJRQOBMKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95303 BRD-K84163249 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95426 BRD-K84163249 U2OS 10 uM 48 h 0.0 0.0 0.0 -0.29 -0.97 0.45
125966 BRD-K84163249 A375 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.89
126033 BRD-K84163249 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126090 BRD-K84163249 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.76 0.07
126138 BRD-K84163249 JURKAT 0.125 uM 24 h -0.25 -1.06 0.24 -0.33 -1.12 0.93
126191 BRD-K84163249 MCF10A 3.33 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
126309 BRD-K84163249 THP1 10 uM 24 h 0.22 0.92 0.04 0.24 0.84 0.12
134071 BRD-K84163249 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
134113 BRD-K84163249 HEK293 0.25 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.49
134186 BRD-K84163249 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134233 BRD-K84163249 MCF??7.00 2.22 uM 24 h 0.19 0.8 0.0 0.27 0.96 0.33
134266 BRD-K84163249 MDAMB231 2.22 uM 24 h -0.19 -0.77 0.0 0.25 0.88 0.18
134289 BRD-K84163249 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.66
134320 BRD-K84163249 YAPC 0.03 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).