CMap Candidate Details

Structure:
CMap ID: C29219
Pert ID: BRD-K84421793
Compound Name: BRD-K84421793
Targets: DRD1
MoA: Dopamine receptor agonist
SMILES: Oc1cc2[C@H](CNCCc2c(Cl)c1O)c3ccccc3
InchiKey: GHWJEDJMOVUXEC-CYBMUJFWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1642 BRD-K84421793 HA1E 10 uM 24 h 0.29 1.22 0.48 0.0 0.0 0.0
1989 BRD-K84421793 HCC515 10 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
2436 BRD-K84421793 PC3 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.35 2.01
2701 BRD-K84421793 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39203 BRD-K84421793 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39353 BRD-K84421793 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39794 BRD-K84421793 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40086 BRD-K84421793 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40350 BRD-K84421793 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.41
40519 BRD-K84421793 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
40893 BRD-K84421793 NEU 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
41214 BRD-K84421793 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41553 BRD-K84421793 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).