CMap Candidate Details

Structure:
CMap ID: C02925
Pert ID: BRD-K01638814
Compound Name: rilmenidine
Targets: NISCH; ADRA2A
MoA: Adrenergic receptor agonist; Imidazoline receptor agonist
SMILES: C1CC1C(NC1=NCCO1)C1CC1
InchiKey: CQXADFVORZEARL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9080 BRD-K01638814 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9329 BRD-K01638814 AGS 10 uM 6 h 0.28 1.17 0.36 0.0 0.0 0.0
9635 BRD-K01638814 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10171 BRD-K01638814 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
10706 BRD-K01638814 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11384 BRD-K01638814 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
11689 BRD-K01638814 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11956 BRD-K01638814 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12240 BRD-K01638814 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12701 BRD-K01638814 SW480 10 uM 6 h 0.23 0.96 0.07 0.0 0.0 0.0
13562 BRD-K01638814 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91019 BRD-K01638814 HUH7 20 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96055 BRD-K01638814 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96453 BRD-K01638814 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96521 BRD-K01638814 PC3 10 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.49
98739 BRD-K01638814 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98857 BRD-K01638814 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122305 BRD-K01638814 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122337 BRD-K01638814 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122401 BRD-K01638814 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122495 BRD-K01638814 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122527 BRD-K01638814 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.49
130640 BRD-K01638814 HEK293 0.01 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
130725 BRD-K01638814 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130749 BRD-K01638814 MCF10A 0.01 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
130797 BRD-K01638814 MDAMB231 0.01 uM 24 h 0.19 0.78 0.0 -0.24 -0.8 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).