CMap Candidate Details

Structure:
CMap ID: C29263
Pert ID: BRD-K84595254
Compound Name: strophanthidin
Targets: ATP1A1
MoA: ATPase inhibitor
SMILES: C[C@@]12CC[C@H]3[C@@H](CC[C@]4(O)C[C@@H](O)CC[C@]34C=O)[C@@]2(O)CC[C@@H]1C5=CC(=O)OC5
InchiKey: ODJLBQGVINUMMR-HZXDTFASSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1787 BRD-K84595254 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1990 BRD-K84595254 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2156 BRD-K84595254 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2458 BRD-K84595254 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44452 BRD-K84595254 A375 10 uM 6 h 0.0 0.0 0.0 -0.51 -1.73 15.65
44730 BRD-K84595254 A549 10 uM 6 h 0.0 0.0 0.0 -0.52 -1.76 15.65
45040 BRD-K84595254 ASC 10 uM 24 h 0.25 1.03 0.13 -0.31 -1.05 0.72
45587 BRD-K84595254 HT29 10 uM 6 h 0.22 0.9 0.03 -0.49 -1.65 15.65
45853 BRD-K84595254 MCF??7.00 10 uM 6 h 0.18 0.76 0.0 -0.4 -1.36 2.02
46152 BRD-K84595254 NPC 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.37 2.02
46793 BRD-K84595254 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53481 BRD-K84595254 HEPG2 4 uM 6 h 0.21 0.86 0.01 -0.4 -1.33 1.85
53619 BRD-K84595254 HUH7 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53697 BRD-K84595254 PHH 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).