CMap Candidate Details

Structure:
CMap ID: C29277
Pert ID: BRD-K84658672
Compound Name: nateglinide
Targets: KCNJ11; ABCC8
MoA: Insulin secretagogue
SMILES: CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
InchiKey: OELFLUMRDSZNSF-ULQDDVLXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4147 BRD-K84658672 HA1E 10 uM 24 h -0.21 -0.86 0.02 0.28 0.98 0.39
4497 BRD-K84658672 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4725 BRD-K84658672 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4966 BRD-K84658672 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
37194 BRD-K84658672 A375 10 uM 6 h 0.0 0.0 0.0 0.21 0.73 0.03
37312 BRD-K84658672 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37750 BRD-K84658672 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37950 BRD-K84658672 HEPG2 10 uM 6 h -0.26 -1.09 0.33 0.0 0.0 0.0
38112 BRD-K84658672 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38225 BRD-K84658672 MCF??7.00 10 uM 24 h -0.25 -1.05 0.23 -0.35 -1.17 1.12
38565 BRD-K84658672 NPC 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.42 2.33
38785 BRD-K84658672 PHH 10 uM 24 h -0.27 -1.11 0.36 -0.22 -0.74 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).