CMap Candidate Details

Structure:
CMap ID: C29285
Pert ID: BRD-K84683831
Compound Name: radezolid
Targets: --
MoA: --
SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
InchiKey: BTTNOGHPGJANSW-IBGZPJMESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95345 BRD-K84683831 MCF??7.00 10 uM 24 h 0.26 1.07 0.2 0.23 0.8 0.08
95388 BRD-K84683831 U2OS 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125967 BRD-K84683831 A375 10 uM 24 h 0.0 0.0 0.0 0.2 0.69 0.01
125986 BRD-K84683831 A549 10 uM 24 h 0.22 0.91 0.04 -0.28 -0.94 0.38
126034 BRD-K84683831 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126091 BRD-K84683831 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126139 BRD-K84683831 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126192 BRD-K84683831 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.75
126242 BRD-K84683831 MDAMB231 10 uM 24 h -0.23 -0.96 0.1 -0.28 -0.95 0.41
126310 BRD-K84683831 THP1 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
134072 BRD-K84683831 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134187 BRD-K84683831 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
134290 BRD-K84683831 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134321 BRD-K84683831 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).