CMap Candidate Details

Structure:
CMap ID: C02929
Pert ID: BRD-K01648091
Compound Name: LE-300
Targets: DRD5
MoA: Dopamine receptor antagonist
SMILES: CN1CCc2c(Cc3ccccc3CC1)[nH]c4ccccc24
InchiKey: YEWGIGCYIAMFMA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4038 BRD-K01648091 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
4335 BRD-K01648091 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4766 BRD-K01648091 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5018 BRD-K01648091 VCAP 10 uM 6 h 0.23 0.95 0.06 -0.31 -1.06 0.72
44278 BRD-K01648091 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
44507 BRD-K01648091 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44813 BRD-K01648091 ASC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
45129 BRD-K01648091 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45399 BRD-K01648091 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45633 BRD-K01648091 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
45930 BRD-K01648091 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46248 BRD-K01648091 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46563 BRD-K01648091 SKB 10 uM 24 h 0.0 0.0 0.0 0.22 0.76 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).