CMap Candidate Details

Structure:
CMap ID: C29363
Pert ID: BRD-K84925803
Compound Name: T-5224
Targets: JUN
MoA: AP inhibitor
SMILES: OC(=O)CCc1cc(ccc1OCc1ccc2c(O)noc2c1)C(=O)c1ccc(OC2CCCC2)cc1O
InchiKey: DALCQQSLNPLQFZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125563 BRD-K84925803 A375 0.04 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
125604 BRD-K84925803 A549 0.125 uM 24 h 0.21 0.87 0.01 -0.35 -1.17 1.14
125637 BRD-K84925803 HEK293 0.37 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
125712 BRD-K84925803 HUVEC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125794 BRD-K84925803 MCF10A 0.04 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
125819 BRD-K84925803 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
125865 BRD-K84925803 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125911 BRD-K84925803 YAPC 0.04 uM 24 h 0.2 0.84 0.0 -0.21 -0.71 0.03
133685 BRD-K84925803 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133752 BRD-K84925803 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133785 BRD-K84925803 HT29 2.22 uM 24 h 0.31 1.28 0.64 0.0 0.0 0.0
133818 BRD-K84925803 JURKAT 2.22 uM 24 h -0.17 -0.72 0.0 -0.21 -0.7 0.03
133900 BRD-K84925803 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
133963 BRD-K84925803 THP1 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).