CMap Candidate Details

Structure:
CMap ID: C02938
Pert ID: BRD-K01674964
Compound Name: histamine
Targets: HRH3; HRH1; HRH2; HRH4
MoA: Histamine receptor agonist
SMILES: NCCc1c[nH]cn1
InchiKey: NTYJJOPFIAHURM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122896 BRD-K01674964 HEK293 0.37 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
123021 BRD-K01674964 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.43 -1.46 15.35
123110 BRD-K01674964 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
123182 BRD-K01674964 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.44
131209 BRD-K01674964 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131245 BRD-K01674964 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131280 BRD-K01674964 HA1E 0.74 uM 24 h 0.17 0.73 0.0 0.0 0.0 0.0
131305 BRD-K01674964 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131327 BRD-K01674964 HT29 2.22 uM 24 h 0.33 1.38 0.97 0.32 1.13 0.84
131358 BRD-K01674964 HUVEC 0.74 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
131398 BRD-K01674964 MCF10A 0.08 uM 24 h -0.17 -0.72 0.0 0.0 0.0 0.0
131437 BRD-K01674964 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
131464 BRD-K01674964 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.08
131496 BRD-K01674964 YAPC 0.01 uM 24 h 0.22 0.9 0.03 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).