CMap Candidate Details

Structure:
CMap ID: C29390
Pert ID: BRD-K84996356
Compound Name: AZD-3514
Targets: --
MoA: --
SMILES: CC(=O)N1CCN(CCOc2ccc(cc2)C2CCN(CC2)C2=Nn3c(CC2)nnc3C(F)(F)F)CC1
InchiKey: JMEYDSHPKCSIJC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90615 BRD-K84996356 HCT116 3.33 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.62
98073 BRD-K84996356 P1A82 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125567 BRD-K84996356 A375 10 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
125605 BRD-K84996356 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125690 BRD-K84996356 HT29 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.69
125716 BRD-K84996356 HUVEC 3.33 uM 24 h 0.27 1.13 0.3 -0.28 -0.93 0.35
125765 BRD-K84996356 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125844 BRD-K84996356 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125915 BRD-K84996356 YAPC 10 uM 24 h 0.23 0.95 0.06 -0.3 -1.02 0.6
133688 BRD-K84996356 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
133726 BRD-K84996356 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133754 BRD-K84996356 HELA 2.22 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
133845 BRD-K84996356 MCF10A 2.22 uM 24 h 0.35 1.47 1.12 -0.22 -0.75 0.06
133876 BRD-K84996356 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
133935 BRD-K84996356 PC3 2.22 uM 24 h 0.16 0.65 0.0 -0.32 -1.07 0.76
133966 BRD-K84996356 THP1 2.22 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).