CMap Candidate Details

Structure:
CMap ID: C29393
Pert ID: BRD-K85013741
Compound Name: auraptene
Targets: MAOB
MoA: Nitric oxide production inhibitor
SMILES: CC(=CCC/C(=C/COc1ccc2ccc(=O)oc2c1)/C)C
InchiKey: RSDDHGSKLOSQFK-RVDMUPIBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3059 BRD-K85013741 HA1E 10 uM 6 h -0.17 -0.72 0.0 -0.26 -0.88 0.24
3273 BRD-K85013741 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
3553 BRD-K85013741 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3879 BRD-K85013741 VCAP 10 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
44454 BRD-K85013741 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44732 BRD-K85013741 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45042 BRD-K85013741 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45330 BRD-K85013741 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45589 BRD-K85013741 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45854 BRD-K85013741 MCF??7.00 10 uM 6 h 0.23 0.98 0.09 -0.31 -1.05 0.69
46154 BRD-K85013741 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46468 BRD-K85013741 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46795 BRD-K85013741 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).