CMap Candidate Details

Structure:
CMap ID: C29432
Pert ID: BRD-K85133207
Compound Name: HDAC1-selective
Targets: --
MoA: --
SMILES: CC(=O)N[C@H]1C[C@H](C1)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1
InchiKey: FTTYFNWRWDLFLP-FZNQNYSPSA-N
Compound Aliases: HDAC-1-SELECTIVE

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
98775 BRD-K85133207 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
98944 BRD-K85133207 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119416 BRD-K85133207 A375 10 uM 24 h -0.26 -1.06 0.26 0.0 0.0 0.0
119448 BRD-K85133207 A549 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
119477 BRD-K85133207 HA1E 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119515 BRD-K85133207 HCC515 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119552 BRD-K85133207 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119582 BRD-K85133207 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119613 BRD-K85133207 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119643 BRD-K85133207 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).