CMap Candidate Details

Structure:
CMap ID: C29479
Pert ID: BRD-K85307935
Compound Name: novobiocin
Targets: --
MoA: --
SMILES: CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C
InchiKey: YJQPYGGHQPGBLI-KGSXXDOSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52204 BRD-K85307935 MCF??7.00 10 uM 6 h 0.34 1.44 1.12 0.0 0.0 0.0
126016 BRD-K85307935 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
126062 BRD-K85307935 HT29 3.33 uM 24 h 0.28 1.15 0.34 0.31 1.09 0.67
126150 BRD-K85307935 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126201 BRD-K85307935 MCF10A 1.11 uM 24 h -0.33 -1.37 1.08 0.33 1.17 0.92
126245 BRD-K85307935 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126272 BRD-K85307935 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126320 BRD-K85307935 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.07
134021 BRD-K85307935 A375 0.74 uM 24 h 0.25 1.02 0.13 0.0 0.0 0.0
134050 BRD-K85307935 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134124 BRD-K85307935 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134165 BRD-K85307935 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134213 BRD-K85307935 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.39 1.37 2.11
134328 BRD-K85307935 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).