CMap Candidate Details

Structure:
CMap ID: C29483
Pert ID: BRD-K85318537
Compound Name: OBAA
Targets: PLA2G1B
MoA: Phospholipase inhibitor
SMILES: CCCCCCCCCCCCCCCCCCc1ccc(cc1)C(=O)/C=C/C(=O)O
InchiKey: ZBESASFHIWDSCJ-WCWDXBQESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1646 BRD-K85318537 HA1E 10 uM 24 h 0.0 0.0 0.0 0.34 1.22 1.15
1996 BRD-K85318537 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2439 BRD-K85318537 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2586 BRD-K85318537 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41851 BRD-K85318537 A375 10 uM 6 h -0.26 -1.07 0.27 0.24 0.84 0.13
41985 BRD-K85318537 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
42487 BRD-K85318537 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42797 BRD-K85318537 HEPG2 10 uM 6 h -0.28 -1.17 0.48 0.0 0.0 0.0
43089 BRD-K85318537 HT29 10 uM 6 h 0.3 1.24 0.51 -0.34 -1.13 0.98
43242 BRD-K85318537 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43662 BRD-K85318537 NPC 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.09
43962 BRD-K85318537 PHH 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.12
44214 BRD-K85318537 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).