CMap Candidate Details

Structure:
CMap ID: C29488
Pert ID: BRD-K85337334
Compound Name: otilonium
Targets: CACNA1C
MoA: Acetylcholine receptor antagonist
SMILES: CCCCCCCCOc1ccccc1C(=O)Nc1ccc(cc1)C(=O)OCC[N+](C)(CC)CC
InchiKey: NQHNLNLJPDMBFN-UHFFFAOYSA-O
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125990 BRD-K85337334 A549 0.37 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
126015 BRD-K85337334 HA1E 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
126061 BRD-K85337334 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126098 BRD-K85337334 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126147 BRD-K85337334 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
126200 BRD-K85337334 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
126318 BRD-K85337334 THP1 10 uM 24 h -0.28 -1.17 0.5 -0.29 -0.99 0.5
126348 BRD-K85337334 YAPC 10 uM 24 h -0.26 -1.08 0.31 0.0 0.0 0.0
134019 BRD-K85337334 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134121 BRD-K85337334 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134163 BRD-K85337334 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134241 BRD-K85337334 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134274 BRD-K85337334 MDAMB231 0.08 uM 24 h 0.28 1.15 0.32 -0.31 -1.05 0.71
134297 BRD-K85337334 PC3 0.74 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).