CMap Candidate Details

Structure:
CMap ID: C00295
Pert ID: BRD-A11609859
Compound Name: SB-205607
Targets: OPRD1
MoA: Delta 1 opioid receptor agonist
SMILES: CN1CCC2(Cc3nc4ccccc4cc3CC2C1)c5cccc(O)c5
InchiKey: LEPBHAAYNPPRRA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1480 BRD-A11609859 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
2028 BRD-A11609859 HCC515 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.38
2317 BRD-A11609859 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2617 BRD-A11609859 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41644 BRD-A11609859 A375 10 uM 6 h -0.2 -0.83 0.0 0.23 0.8 0.08
41869 BRD-A11609859 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42174 BRD-A11609859 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42519 BRD-A11609859 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42829 BRD-A11609859 HT29 10 uM 6 h -0.26 -1.09 0.33 0.24 0.83 0.12
43251 BRD-A11609859 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.62
43375 BRD-A11609859 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43691 BRD-A11609859 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43990 BRD-A11609859 SKB 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).