CMap Candidate Details

Structure:
CMap ID: C29535
Pert ID: BRD-K85518562
Compound Name: cilastatin
Targets: DPEP1
MoA: Dehydropeptidase inhibitor
SMILES: CC1(C)C[C@@H]1C(=O)N/C(=CCCCCSC[C@H](N)C(=O)O)/C(=O)O
InchiKey: DHSUYTOATWAVLW-WFVMDLQDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24493 BRD-K85518562 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24698 BRD-K85518562 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24818 BRD-K85518562 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24958 BRD-K85518562 HT29 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.58
25113 BRD-K85518562 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.86 0.21
25198 BRD-K85518562 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25540 BRD-K85518562 VCAP 10 uM 6 h -0.24 -0.99 0.14 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).