CMap Candidate Details
Structure:
CMap ID: | C29646 |
Pert ID: | BRD-K85853281 |
Compound Name: | BRD-K85853281 |
Targets: | TOP2A |
MoA: | Topoisomerase inhibitor |
SMILES: | C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@@H]1C[C@](O)(Cc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c12)C(C)=O |
InchiKey: | XDXDZDZNSLXDNA-LGVQOGFTSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
21922 | BRD-K85853281 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.16 | 0.9 |
22169 | BRD-K85853281 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
22580 | BRD-K85853281 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
22864 | BRD-K85853281 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.43 | 1.53 | 2.3 |
23167 | BRD-K85853281 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
23455 | BRD-K85853281 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.37 | 1.3 | 1.49 |
23646 | BRD-K85853281 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
23902 | BRD-K85853281 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
115200 | BRD-K85853281 | U2OS | 20 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.23 | 0.82 | 0.1 |