CMap Candidate Details

Structure:
CMap ID: C29652
Pert ID: BRD-K85871428
Compound Name: SC-68376
Targets: MAPK14
MoA: P38 MAPK inhibitor
SMILES: Cc1nc(c(o1)c2ccncc2)c3ccccc3
InchiKey: BHWCZLOXTLWZAQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3061 BRD-K85871428 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3275 BRD-K85871428 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3555 BRD-K85871428 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
3881 BRD-K85871428 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
39207 BRD-K85871428 A375 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.6
39356 BRD-K85871428 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39800 BRD-K85871428 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40092 BRD-K85871428 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.31
40356 BRD-K85871428 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40651 BRD-K85871428 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.41 2.02
40899 BRD-K85871428 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41220 BRD-K85871428 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41559 BRD-K85871428 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).