CMap Candidate Details

Structure:
CMap ID: C29747
Pert ID: BRD-K86191271
Compound Name: cytosporone-b
Targets: NR4A1
MoA: NUR77 receptor agonist
SMILES: CCCCCCCC(=O)c1c(O)cc(O)cc1CC(=O)OCC
InchiKey: UVVWQQKSNZLUQA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8999 BRD-K86191271 A375 10 uM 24 h -0.2 -0.85 0.01 0.29 1.03 0.5
9247 BRD-K86191271 A549 10 uM 6 h 0.0 0.0 0.0 0.21 0.75 0.04
9530 BRD-K86191271 AGS 10 uM 6 h 0.21 0.88 0.02 0.0 0.0 0.0
9835 BRD-K86191271 H1299 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
10089 BRD-K86191271 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10354 BRD-K86191271 HCC515 10 uM 6 h 0.0 0.0 0.0 0.15 0.55 0.0
10612 BRD-K86191271 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10865 BRD-K86191271 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11027 BRD-K86191271 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11233 BRD-K86191271 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11597 BRD-K86191271 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.16 1.11
12154 BRD-K86191271 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12395 BRD-K86191271 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12633 BRD-K86191271 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13092 BRD-K86191271 THP1 10 uM 6 h 0.0 0.0 0.0 0.32 1.15 0.88
13378 BRD-K86191271 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13692 BRD-K86191271 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.13 0.98
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).