CMap Candidate Details

Structure:
CMap ID: C29799
Pert ID: BRD-K86354270
Compound Name: BRD-K86354270
Targets: --
MoA: --
SMILES: OC[C@@H]1[C@@H]([C@H](C#N)N1C(=O)Nc1ccc(F)cc1)c1ccc(cc1)-c1cccnc1
InchiKey: OSGUSCSJMGIYLG-BHDDXSALSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
60453 BRD-K86354270 VCAP 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
85822 BRD-K86354270 A375 20 uM 24 h 0.29 1.19 0.42 -0.2 -0.66 0.01
85904 BRD-K86354270 A549 20 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
86008 BRD-K86354270 HA1E 20 uM 24 h 0.21 0.86 0.01 -0.37 -1.26 1.35
86115 BRD-K86354270 HCC515 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
86222 BRD-K86354270 HEPG2 20 uM 24 h 0.17 0.73 0.0 0.0 0.0 0.0
86318 BRD-K86354270 HT29 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.43
86399 BRD-K86354270 MCF??7.00 20 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.58
86489 BRD-K86354270 PC3 20 uM 24 h -0.18 -0.75 0.0 0.28 1.01 0.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).