CMap Candidate Details

Structure:
CMap ID: C00298
Pert ID: BRD-A11706664
Compound Name: triciribine
Targets: AKT3; AKT1; AKT2
MoA: Akt inhibitor
SMILES: Cn1nc(N)c2cn([C@@H]3O[C@H](CO)C(O)[C@@H]3O)c3ncnc1c23
InchiKey: HOGVTUZUJGHKPL-XVCUJNKASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33726 BRD-A11706664 A375 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
33740 BRD-A11706664 A549 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
33973 BRD-A11706664 ASC 10 uM 24 h -0.19 -0.79 0.0 -0.29 -0.97 0.46
34256 BRD-A11706664 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
34489 BRD-A11706664 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35036 BRD-A11706664 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35265 BRD-A11706664 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35668 BRD-A11706664 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36037 BRD-A11706664 PC3 10 uM 6 h 0.16 0.67 0.0 -0.38 -1.27 1.44
36133 BRD-A11706664 PHH 10 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
36427 BRD-A11706664 SKB 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
36925 BRD-A11706664 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).