CMap Candidate Details

Structure:
CMap ID: C29858
Pert ID: BRD-K86595100
Compound Name: chlordiazepoxide
Targets: GABRA1; GABRA2; GABRA3; GABRA4; GABRA5; GABRA6; GABRB1; GABRB2; GABRB3; GABRD; GABRE; GABRG1; GABRG2; GABRG3; GABRP; GABRQ
MoA: Benzodiazepine receptor agonist
SMILES: CNC1=Nc2ccc(Cl)cc2C(=[N+]([O-])C1)c3ccccc3
InchiKey: ANTSCNMPPGJYLG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22349 BRD-K86595100 A549 10 uM 6 h -0.16 -0.69 0.0 0.0 0.0 0.0
22584 BRD-K86595100 HA1E 10 uM 6 h -0.27 -1.14 0.42 0.0 0.0 0.0
22868 BRD-K86595100 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.25
23170 BRD-K86595100 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23459 BRD-K86595100 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23762 BRD-K86595100 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23905 BRD-K86595100 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24227 BRD-K86595100 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).