CMap Candidate Details

Structure:
CMap ID: C29860
Pert ID: BRD-K86600316
Compound Name: RS-79948
Targets: ADRA2A
MoA: Adrenergic receptor antagonist
SMILES: CCS(=O)(=O)N1CCC[C@@H]2CN3CCc4cc(OC)ccc4[C@@H]3C[C@H]12
InchiKey: UMGBFFAJXFXOIL-MNEFBYGVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6808 BRD-K86600316 A375 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.03 0.62
7197 BRD-K86600316 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7488 BRD-K86600316 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7724 BRD-K86600316 HCC515 10 uM 6 h -0.29 -1.2 0.57 0.0 0.0 0.0
7921 BRD-K86600316 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8115 BRD-K86600316 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.12
8532 BRD-K86600316 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8730 BRD-K86600316 VCAP 10 uM 24 h -0.18 -0.77 0.0 -0.34 -1.15 1.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).