CMap Candidate Details

Structure:
CMap ID: C02987
Pert ID: BRD-K01824921
Compound Name: DPCPX
Targets: ADORA1
MoA: Adenosine receptor antagonist
SMILES: CCCn1c2[nH]c(nc2c(=O)n(CCC)c1=O)C1CCCC1
InchiKey: FFBDFADSZUINTG-UHFFFAOYSA-N
Compound Aliases: dpcpx

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96484 BRD-K01824921 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99964 BRD-K01824921 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
122847 BRD-K01824921 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122898 BRD-K01824921 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122974 BRD-K01824921 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123023 BRD-K01824921 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.05
123112 BRD-K01824921 MDAMB231 10 uM 24 h 0.34 1.41 1.03 0.24 0.84 0.13
123184 BRD-K01824921 THP1 1.11 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.12
131281 BRD-K01824921 HA1E 0.74 uM 24 h 0.25 1.02 0.13 0.0 0.0 0.0
131307 BRD-K01824921 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.38 1.33 1.72
131360 BRD-K01824921 HUVEC 0.08 uM 24 h 0.29 1.22 0.48 0.34 1.19 1.02
131400 BRD-K01824921 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131438 BRD-K01824921 MCF??7.00 0.01 uM 24 h -0.24 -0.98 0.12 -0.29 -0.99 0.5
131465 BRD-K01824921 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.12
131498 BRD-K01824921 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).