CMap Candidate Details

Structure:
CMap ID: C29922
Pert ID: BRD-K86816506
Compound Name: PF-04457845
Targets: FAAH
MoA: FAAH inhibitor
SMILES: FC(F)(F)c1ccc(Oc2cccc(C=C3CCN(CC3)C(=O)Nc3cccnn3)c2)nc1
InchiKey: BATCTBJIJJEPHM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96855 BRD-K86816506 A375 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
125993 BRD-K86816506 A549 10 uM 24 h -0.3 -1.27 0.73 0.0 0.0 0.0
126042 BRD-K86816506 HELA 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
126065 BRD-K86816506 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126104 BRD-K86816506 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
126159 BRD-K86816506 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
126210 BRD-K86816506 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126227 BRD-K86816506 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126278 BRD-K86816506 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126329 BRD-K86816506 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
126351 BRD-K86816506 YAPC 10 uM 24 h -0.2 -0.85 0.01 0.2 0.7 0.02
134079 BRD-K86816506 HA1E 0.03 uM 24 h -0.2 -0.82 0.0 -0.34 -1.15 1.07
134133 BRD-K86816506 HEK293 2.22 uM 24 h 0.0 0.0 0.0 -0.5 -1.68 15.65
134278 BRD-K86816506 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).