CMap Candidate Details

Structure:
CMap ID: C29948
Pert ID: BRD-K86887724
Compound Name: dofetilide
Targets: KCNH2
MoA: Potassium channel blocker
SMILES: CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc(NS(C)(=O)=O)cc1
InchiKey: IXTMWRCNAAVVAI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24496 BRD-K86887724 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24620 BRD-K86887724 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24961 BRD-K86887724 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25052 BRD-K86887724 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25200 BRD-K86887724 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25437 BRD-K86887724 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90990 BRD-K86887724 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).