CMap Candidate Details

Structure:
CMap ID: C03001
Pert ID: BRD-K01877528
Compound Name: TL-HRAS-61
Targets: --
MoA: --
SMILES: Cc1onc(C(=O)N2CCN(CC2)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)c1[N+]([O-])=O
InchiKey: VIBHJPDPEVVDTB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9331 BRD-K01877528 AGS 10 uM 6 h 0.25 1.05 0.17 0.0 0.0 0.0
10180 BRD-K01877528 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10927 BRD-K01877528 HT29 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
11183 BRD-K01877528 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.69 0.02
11387 BRD-K01877528 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11959 BRD-K01877528 NCIH596 10 uM 6 h -0.35 -1.45 1.43 -0.31 -1.04 0.67
12242 BRD-K01877528 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12704 BRD-K01877528 SW480 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.26
13184 BRD-K01877528 U937 10 uM 6 h 0.27 1.14 0.32 -0.39 -1.31 1.71
13564 BRD-K01877528 VCAP 10 uM 6 h 0.22 0.91 0.03 0.0 0.0 0.0
18391 BRD-K01877528 PC3 10 uM 6 h -0.21 -0.87 0.02 0.0 0.0 0.0
96187 BRD-K01877528 A549 10 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
96256 BRD-K01877528 U2OS 1.11 uM 24 h 0.23 0.97 0.08 -0.25 -0.85 0.19
119171 BRD-K01877528 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119229 BRD-K01877528 HA1E 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119519 BRD-K01877528 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).