CMap Candidate Details

Structure:
CMap ID: C30017
Pert ID: BRD-K87048468
Compound Name: RS-102221
Targets: HTR2C
MoA: Serotonin receptor antagonist
SMILES: COc1cc(OC)c(cc1NS(=O)(=O)c1ccc(cc1)C(F)(F)F)C(=O)CCCCN1CCC2(CC1)NC(=O)NC2=O
InchiKey: HZZZZODVDSHQRG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2934 BRD-K87048468 HA1E 10 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
3278 BRD-K87048468 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3557 BRD-K87048468 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3884 BRD-K87048468 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39208 BRD-K87048468 A375 10 uM 6 h 0.0 0.0 0.0 0.33 1.17 0.92
39357 BRD-K87048468 A549 10 uM 24 h -0.26 -1.1 0.35 -0.36 -1.21 1.24
39802 BRD-K87048468 ASC 10 uM 24 h 0.3 1.25 0.54 0.0 0.0 0.0
40094 BRD-K87048468 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40359 BRD-K87048468 HT29 10 uM 6 h -0.19 -0.78 0.0 0.24 0.85 0.14
40522 BRD-K87048468 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40902 BRD-K87048468 NEU 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
41223 BRD-K87048468 NPC 10 uM 24 h -0.26 -1.08 0.3 0.0 0.0 0.0
41562 BRD-K87048468 SKB 10 uM 24 h -0.26 -1.07 0.28 0.19 0.69 0.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).