CMap Candidate Details

Structure:
CMap ID: C30018
Pert ID: BRD-K87049188
Compound Name: fusaric-acid
Targets: DBH
MoA: Dopamine beta hydroxylase inhibitor
SMILES: CCCCc1ccc(nc1)C(=O)O
InchiKey: DGMPVYSXXIOGJY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1649 BRD-K87049188 HA1E 10 uM 24 h 0.28 1.17 0.36 0.0 0.0 0.0
2134 BRD-K87049188 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
2214 BRD-K87049188 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2705 BRD-K87049188 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39209 BRD-K87049188 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39511 BRD-K87049188 A549 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.69 0.02
39803 BRD-K87049188 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40095 BRD-K87049188 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
40360 BRD-K87049188 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40654 BRD-K87049188 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41224 BRD-K87049188 NPC 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.36
41563 BRD-K87049188 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).