CMap Candidate Details

Structure:
CMap ID: C30060
Pert ID: BRD-K87156652
Compound Name: carbimazole
Targets: TPO
MoA: Anti-thyroid agent
SMILES: CCOC(=O)n1ccn(C)c1=S
InchiKey: CFOYWRHIYXMDOT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96470 BRD-K87156652 A375 1.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127771 BRD-K87156652 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127811 BRD-K87156652 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
127849 BRD-K87156652 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127923 BRD-K87156652 HUVEC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127977 BRD-K87156652 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.67
128042 BRD-K87156652 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135550 BRD-K87156652 HELA 0.01 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
135599 BRD-K87156652 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135641 BRD-K87156652 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
135688 BRD-K87156652 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135736 BRD-K87156652 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).