CMap Candidate Details

Structure:
CMap ID: C03008
Pert ID: BRD-K01902415
Compound Name: pirinixic-acid
Targets: PPARA
MoA: PPAR receptor agonist
SMILES: Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C
InchiKey: SZRPDCCEHVWOJX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4182 BRD-K01902415 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4338 BRD-K01902415 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.62
4634 BRD-K01902415 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5020 BRD-K01902415 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44279 BRD-K01902415 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44657 BRD-K01902415 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44815 BRD-K01902415 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45634 BRD-K01902415 MCF??7.00 10 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
46565 BRD-K01902415 SKB 10 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
52762 BRD-K01902415 HEPG2 20 uM 24 h 0.25 1.03 0.14 0.24 0.87 0.17
98740 BRD-K01902415 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
98858 BRD-K01902415 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).