CMap Candidate Details

Structure:
CMap ID: C30119
Pert ID: BRD-K87343924
Compound Name: wortmannin
Targets: PIK3CA; PIK3CG; PLK1
MoA: PI3K inhibitor
SMILES: COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C([C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O)C3=O
InchiKey: QDLHCMPXEPAAMD-QAIWCSMKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5806 BRD-K87343924 HCC515 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.03
6598 BRD-K87343924 VCAP 10 uM 6 h 0.23 0.98 0.09 0.0 0.0 0.0
115982 BRD-K87343924 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116023 BRD-K87343924 A549 0.04 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
116062 BRD-K87343924 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116152 BRD-K87343924 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116196 BRD-K87343924 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116232 BRD-K87343924 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116272 BRD-K87343924 PC3 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.44 15.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).