CMap Candidate Details

Structure:
CMap ID: C30175
Pert ID: BRD-K87510569
Compound Name: RS-504393
Targets: CCR2
MoA: CCK receptor antagonist
SMILES: Cc1oc(nc1CCN1CCC2(CC1)OC(=O)Nc1ccc(C)cc21)-c1ccccc1
InchiKey: ODNICNWASXKNNQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1650 BRD-K87510569 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1999 BRD-K87510569 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2161 BRD-K87510569 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2645 BRD-K87510569 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39210 BRD-K87510569 A375 10 uM 6 h -0.27 -1.13 0.41 -0.28 -0.96 0.43
39358 BRD-K87510569 A549 10 uM 24 h 0.28 1.17 0.37 0.34 1.21 1.15
39804 BRD-K87510569 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40096 BRD-K87510569 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40361 BRD-K87510569 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40523 BRD-K87510569 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40903 BRD-K87510569 NEU 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
41225 BRD-K87510569 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41564 BRD-K87510569 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).