CMap Candidate Details

Structure:
CMap ID: C30191
Pert ID: BRD-K87555556
Compound Name: amiodarone
Targets: KCNH2
MoA: Potassium channel blocker
SMILES: CCCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1
InchiKey: QMKSCTINHJSWPD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49905 BRD-K87555556 A375 10 uM 6 h 0.0 0.0 0.0 0.26 0.94 0.28
50072 BRD-K87555556 A549 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.7
50256 BRD-K87555556 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50603 BRD-K87555556 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50693 BRD-K87555556 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50870 BRD-K87555556 PC3 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
51189 BRD-K87555556 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).