CMap Candidate Details

Structure:
CMap ID: C30194
Pert ID: BRD-K87573634
Compound Name: propylpyrazole
Targets: ESR1
MoA: Estrogen receptor agonist
SMILES: CCCc1cn(nc1-c1ccc(O)cc1)-c1ccc(O)cc1
InchiKey: HTMIOGNQDXQXAQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25650 BRD-K87573634 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26169 BRD-K87573634 A549 10 uM 6 h 0.25 1.04 0.16 0.0 0.0 0.0
26487 BRD-K87573634 ASC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
26808 BRD-K87573634 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
27108 BRD-K87573634 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27419 BRD-K87573634 HT29 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.61
27623 BRD-K87573634 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28049 BRD-K87573634 NEU 10 uM 24 h 0.0 0.0 0.0 0.19 0.66 0.01
28369 BRD-K87573634 NPC 10 uM 24 h -0.25 -1.03 0.2 -0.26 -0.87 0.23
28537 BRD-K87573634 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28998 BRD-K87573634 PHH 10 uM 24 h -0.24 -1.01 0.16 -0.42 -1.43 15.35
29339 BRD-K87573634 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29689 BRD-K87573634 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).