CMap Candidate Details

Structure:
CMap ID: C03024
Pert ID: BRD-K01976263
Compound Name: emetine
Targets: RPS2
MoA: Protein synthesis inhibitor
SMILES: N[C@@H](CCl)C(=O)O
InchiKey: ASBJGPTTYPEMLP-REOHCLBHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8896 BRD-K01976263 A375 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9081 BRD-K01976263 A549 0.66 uM 24 h 0.32 1.35 0.94 0.0 0.0 0.0
9332 BRD-K01976263 AGS 0.66 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.61
9638 BRD-K01976263 H1299 0.66 uM 6 h 0.0 0.0 0.0 -0.3 -0.99 0.51
10022 BRD-K01976263 HA1E 0.66 uM 6 h 0.29 1.23 0.5 0.0 0.0 0.0
10227 BRD-K01976263 HCC515 0.66 uM 24 h 0.34 1.41 1.03 -0.25 -0.83 0.16
10436 BRD-K01976263 HCT116 0.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10709 BRD-K01976263 HEPG2 0.66 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
11109 BRD-K01976263 HT29 0.66 uM 6 h 0.2 0.82 0.0 -0.44 -1.48 15.35
11388 BRD-K01976263 NCIH2073 0.66 uM 6 h 0.0 0.0 0.0 -0.5 -1.67 15.65
11692 BRD-K01976263 NCIH508 0.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11960 BRD-K01976263 NCIH596 0.66 uM 6 h 0.0 0.0 0.0 -0.47 -1.58 15.65
12243 BRD-K01976263 NOMO1 0.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12551 BRD-K01976263 PC3 0.66 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
12705 BRD-K01976263 SW480 0.66 uM 6 h 0.0 0.0 0.0 -0.35 -1.18 1.15
13185 BRD-K01976263 U937 0.66 uM 6 h 0.26 1.09 0.23 -0.23 -0.78 0.1
13438 BRD-K01976263 VCAP 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90580 BRD-K01976263 MCF??7.00 1.11 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).