CMap Candidate Details
Structure:
| CMap ID: | C30249 |
| Pert ID: | BRD-K87774949 |
| Compound Name: | istradefylline |
| Targets: | ADORA1; ADORA2A |
| MoA: | Adenosine receptor antagonist |
| SMILES: | CCn1c2nc(C=Cc3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O |
| InchiKey: | IQVRBWUUXZMOPW-PKNBQFBNSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96982 | BRD-K87774949 | A375 | 3.33 uM | 24 h | -0.21 | -0.87 | 0.03 | 0.0 | 0.0 | 0.0 |
| 97061 | BRD-K87774949 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.89 | 0.26 |